Gene interactions and pathways from curated databases and text-mining

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IGF1R — MAPK11

Text-mined interactions from Literome

Song et al., Proc Natl Acad Sci U S A 2004 : Down-regulation of Shc, ERalpha, or IGF-1R with specific small inhibitory RNAs all blocked E2-induced mitogen activated protein kinase phosphorylation
Kataoka et al., J Radiat Res 2004 : We have investigated the role of insulin-like growth factor I receptor ( IGF-IR ) in heat shock induced activation of the mitogen activated protein kinase ( MAPK ) and phosphatidylinositol-3 ' kinase (PI3-K) pathways
Lewis et al., J Invest Dermatol 2008 : We hypothesize that UVB irradiation leads to an activated p38 MAPK that is regulated in an IGF-1R dependent manner, leading to NF-kappaB p50 : RelA/p65 activation and a survival phenotype
Luttrell et al., J Biol Chem 1995 : G beta gamma subunits mediate mitogen activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor