Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
KRT8
→
MAPK8
(directlyIncreases, KRT8 Activity)
He et al., J Biol Chem 2002* Evidence: One example is K8 Ser-73, which has been implicated as an important phosphorylation site during mitosis, cell stress, and apoptosis. We show that K8 is strongly phosphorylated on Ser-73 upon stimulation of the pro-apoptotic cytokine receptor Fas/CD95/Apo-1 in HT-29 cells. Kinase assays showed that c-Jun N-terminal kinase (JNK) was also activated with activation kinetics corresponding to that of K8 phosphorylation. Furthermore, K8 was also phosphorylated on Ser-73 by JNK in vitro, yielding simila...
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *