Ganey et al., Exp Lung Res 1987
(Body Weight...) :
Damage to endothelial cells in culture has been associated with altered prostacyclin ( PGI2 ) production ; therefore, it was of interest to determine if MCTP affected pulmonary PGI2 production
Taylor et al., Toxicol Appl Pharmacol 1997
:
MCTP caused increased LDH release by 48 hr, augmented PGI2 synthesis by 96 hr, and resulted in hypertrophy and decreased cell density by 48 hr that persisted at least 21 days