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MMP1 — POLDIP2

Text-mined interactions from Literome

Westermarck et al., Cancer Res 2000 (Carcinoma, Squamous Cell...) : Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen activated protein kinase and c-Jun NH2-terminal kinase-2 ... The induction of MMP-1 expression correlates with activation of c-Jun NH2-terminal kinase (JNK) and p38 mitogen activated protein kinase and phosphorylation of c-Jun and activating transcription factor-2 ( ATF-2 ) and is dependent on the activity of p38 mitogen activated protein kinase
Fan et al., Rheumatol Int 2006 : Our data suggest that ERK and NFkB pathways are particularly important for IL-1beta regulating collagen type II and MMP-1 and -13 expression and that p38 , but not JNK is additionally involved in MMP-1 and -13 induction
Kunisch et al., Ann Rheum Dis 2007 (Arthritis, Rheumatoid...) : Strikingly, RA-SFB are insensitive to p38 inhibition of MMP-1 secretion
Junttila et al., Oncogene 2007 (Carcinoma, Squamous Cell...) : Inhibition of endogenous p38alpha or p38delta activity by adenoviral delivery of corresponding dominant negative p38 isoforms potently reduced MMP-13 and MMP-1 expressions, and suppressed the invasion of HNSCC cells through collagen
Papazoglou et al., Br J Dermatol 2011 : Our studies in HDFs demonstrated that both a Syk inhibitor and Syk siRNA were able to inhibit MMP-1 expression in HDFs exposed to UV and that overexpression of Syk increased MMP-1 expression and the activity of JNK kinase, but not p38 or Erk1/2 MAP kinase
Lim et al., FEBS Lett 1998 (Carcinoma, Non-Small-Cell Lung...) : That p38 activity was required for EMMPRIN stimulation of MMP-1 was evident from results showing that the p38 inhibitor SB203580 blocked this response