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IL6 — MT4
Text-mined interactions from Literome
Molotkov et al., Life Sci 2000
:
Role of
IL-6 in the induction of hepatic
metallothionein in mice after partial hepatectomy
Ashino et al., Eur J Pharmacol 2007
(Arthritis, Rheumatoid) :
The present study has revealed that CYP3A11 and
metallothionein expressions are
affected by the release of
IL-6 by arthritis and its systemic circulation, and neutralization of IL-6 recovered from the down-regulation of CYP3A11 mRNA and the induction of metallothionein mRNA in arthritic HTLV-I transgenic mice
Schroeder et al., Proc Natl Acad Sci U S A 1990
:
Interleukin 6 regulates
metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures ... We have evaluated the
effects of
IL-6 and IL-1 alpha as well as extracellular zinc and glucocorticoid hormone on
metallothionein gene expression and cellular zinc accumulation in rat hepatocyte monolayer cultures
Cousins et al., FASEB J 1988
(Acute-Phase Reaction) :
Tissue-specific
regulation of zinc metabolism and
metallothionein genes by
interleukin 1
Snyers et al., Eur J Biochem 1994
:
Induction of
metallothionein and stomatin by
interleukin-6 and glucocorticoids in a human amniotic cell line ... In UAC cells both
metallothionein and stomatin are
induced by dexamethasone and
IL-6 in a more than additive manner
Itoh et al., Toxicol Appl Pharmacol 1994
:
n-hexane induced synthesis of hepatic
metallothionein is
mediated by
IL-6 in mouse
Sato et al., Int J Immunopharmacol 1994
:
Differential
induction of
metallothionein synthesis by
interleukin-6 and tumor necrosis factor-alpha in rat tissues
Bauer et al., J Neuroimmunol 1993
(Neuroblastoma) :
Effects of
interleukin-1 and interleukin-6 on
metallothionein and amyloid precursor protein expression in human neuroblastoma cells ... We found that interleukin-6 and
interleukin-1 induced
metallothionein expression in a human neuronal ( SH-SY5Y neuroblastoma ) cell line
Kikuchi et al., FEBS Lett 1993
(Astrocytoma) :
Induction of
metallothionein in a human astrocytoma cell line by
interleukin-1 and heavy metals
Sato et al., Int J Immunopharmacol 1996
:
Synergistic
induction of
metallothionein synthesis by
interleukin-6 , dexamethasone and zinc in the rat ... We investigated the reciprocal
effects of
interleukin-6 (IL-6) , glucocorticoid and zinc ( Zn ) on
metallothionein ( MT ) synthesis in rats
Hernández et al., Brain Res Mol Brain Res 1997
:
Transgenic expression of
interleukin 6 in the central nervous system
regulates brain
metallothionein-I and -III expression in mice
Carrasco et al., Brain Res Mol Brain Res 1998
:
Interleukin-6 and tumor necrosis factor-alpha type 1 receptor deficient mice reveal a
role of
IL-6 and TNF-alpha on brain
metallothionein-I and -III regulation
Kasutani et al., Toxicol Appl Pharmacol 1998
:
Requirement for cooperative interaction of interleukin-6 responsive element type 2 and glucocorticoid responsive element in the synergistic
activation of mouse
metallothionein-I gene by
interleukin-6 and glucocorticoid