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Moreno et al., Ann Neurol 2006
(Disease Models, Animal...) :
Indeed, MTA suppressed the production of proinflammatory genes and cytokines ( interferon-gamma, tumor necrosis factor-alpha, and inducible nitric oxide synthase ) and increased the production of antiinflammatory cytokines ( interleukin-10 )
Minamikawa et al., J Endod 2009
:
MTA significantly caused an up-regulation of cyclooxygenase-2 (COX-2) and inducible form of nitric oxide synthase ( iNOS ) mRNA expression