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APC — MYLIP

Text-mined interactions from Literome

Zheng et al., Plant Cell 2011 : We show that these apc/c mutants had reduced miR159 levels and increased DUO1 and CYCB1 ; 1 transcript levels and that APC/C is required to recruit RNA polymerase II to MIR159 promoters ... Thus, in addition to its role in degrading CYCB1 ; 1, APC/C stimulates production of miR159 , which downregulates DUO1 expression, leading to reduced CYCB1 ; 1 transcription ... Both MIR159 and APC8-yellow fluorescent protein accumulated in unicellular microspores and bicellular pollen but decreased in tricellular pollen, suggesting that spatial and temporal regulation of miR159 by APC/C ensures mitotic progression
Holleman et al., Oncogene 2011 (Carcinoma, Non-Small-Cell Lung...) : Our results indicate that paclitaxel resistance is associated with upregulation of miR-135a, both in vitro and in vivo, and is in part determined by miR-135a mediated downregulation of APC
Zhang et al., J Clin Endocrinol Metab 2013 (Carcinoma...) : By targeting APC , miR-155 efficiently regulates the Wnt/ß-catenin signaling