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IL6 — NAALADL1
Text-mined interactions from Literome
Pedersen et al., Scand J Immunol 2005
(Breast Neoplasms) :
The lymph node homing chemokine receptor CCR-7 expression was induced by TNF-alpha + IL-1beta +
IL-6 + prostaglandin E2 but was not
induced by Poly
I:C + TNF-alpha
Gandhi et al., Brain Behav Immun 2007
:
In naïve mice, poly
I:C ( 2mg/kg ) modestly
increased sickness behaviors, plasma
IL-6 , TNF-alpha and IL-10 levels, but did not affect IL-1, IL-4, or IFN-gamma
Vuckovic et al., Clin Immunol 2007
(Celiac Disease...) :
Blood DC in T1D patients were not distinguished from those of controls by the levels of HLA-DR, CD40 and CD86 expression or the percentage of DC expressing cytokines, IL-12, IL-10,
IL-6 and TNF-alpha, in
responses to poly
I:C
Ospelt et al., Arthritis Rheum 2008
(Arthritis, Rheumatoid...) :
Among the expressed TLRs, TLR-3 and TLR-4 were the most abundant in synovial fibroblasts, and stimulation of synovial fibroblasts with the TLR-3 ligand poly (
I-C )
led to the most pronounced increase in
IL-6 , MMP-3, and MMP-13
Into et al., Cell Immunol 2010
(Bacterial Infections...) :
LL-37 potently suppressed LPS induced gene expression of IL6, IL8 and CXCL10 and intracellular signaling events, degradation of IRAK-1 and IkappaBalpha and phosphorylation of p38 MAPK and IRF3, indicating that the LPS neutralizing activity is also exerted in HGFs. LL-37 also suppressed the expression of
IL6 , IL8 and CXCL10
induced by the TLR3 ligand poly (
I:C )
McLinden et al., Physiol Behav 2012
:
Furthermore, we observed an increase in peripheral poly
I:C induced
IL-6 , TNF-a, MCP-1, and MIP-1a, but not IL-1ß
Rautava et al., J Pediatr Gastroenterol Nutr 2012
:
Conditioning with TGF-ß2 significantly attenuated subsequent interleukin (IL)-1ß-, TNF-a-, and poly
I:C induced IL-8 and
IL-6 responses in immature human IECs
Qin et al., Journal of neuroinflammation 2012
(Inflammation...) :
Ethanol pretreatment potentiated poly
I:C induced brain TNFa ( 345 % ), IL-1ß ( 331 % ),
IL-6 ( 255 % ), and MCP-1 ( 190 % )
Ro et al., Cell Transplant 2013
:
Both poly
I:C and LPS stimulation in porcine islets
induced expression of chemokines ( RANTES, MCP-1, IP-10, and IL-8 ), cytokines (
IL-6 and type I interferons ), and adhesion molecules ( VCAM-1 and ICAM-1 )
Yang et al., Proc Natl Acad Sci U S A 2013
:
Consistently, production of IFN-ß, CCL5, TNFa, and
IL-6 in
response to the TLR3 ligand poly (
I:C ) was elevated in Wwp2 ( -/- ) macrophages and Wwp2-deficient mice exhibited increased susceptibility to poly ( I:C ) -induced death than the control littermates