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NFKB1 — RAC2

Pathways - manually collected, often from reviews:

• KEGG Pancreatic cancer: RAC1/RAC2/RAC3 → NFKB1/RELA (protein-protein, activation)

Text-mined interactions from Literome

Huttunen et al., J Biol Chem 1999 (Neuroblastoma) : In contrast, the activation of NF-kappaB is inhibited by dominant negative Ras but not Rac or Cdc42
Cammarano et al., J Biol Chem 2001 : Here we show that although Dbl activation of NF kappa B requires Cdc42, Rac , and Rho, the different GTPases activate NF kappa B by different mechanisms
Wroblewski et al., J Cell Sci 2003 (Neoplasm Invasiveness) : RhoA acted through activation of both NF-kappaB and AP-1, whereas Rac activated NF-kappaB but not AP-1