Gene interactions and pathways from curated databases and text-mining

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APCS — NOD2

Text-mined interactions from Literome

Penack et al., J Exp Med 2009 (Colitis...) : We found that proliferation and activation of donor T cells was enhanced in NOD-deficient allo-BMT recipients, suggesting that NOD2 plays a role in the regulation of host antigen presenting cells (APCs)
Zaccone et al., J Biomed Biotechnol 2010 (Diabetes Mellitus, Type 1...) : We have shown that Schistosoma mansoni egg soluble antigen (SEA) prevents diabetes in the nonobese diabetic ( NOD ) mouse inducing functional changes in antigen presenting cells (APCs) and expanding T helper ( Th ) 2 and regulatory T cell ( Treg ) responses