◀ Back to MYC
MYC — PCNA
Text-mined interactions from Literome
Warner et al., Mol Cell Biol 1999
:
c-Myc causes a small increase in
cyclin D levels, but this effect contributes little to the loss of TGF-beta responses in these cells
Neve et al., Oncogene 2000
(Breast Neoplasms...) :
Ectopic expression of
c-Myc led to an increase in D
cyclin levels, CDK2 activity and resulted in a partial G1 rescue
Beier et al., EMBO J 2000
:
Induction of
cyclin E-cdk2 kinase activity, E2F dependent transcription and cell growth by
Myc are genetically separable events
Deb-Basu et al., Cell cycle (Georgetown, Tex.) 2006
:
We have found that
cyclin dependent kinase 2 (CDK2) is
required by
MYC to induce apoptosis
Jansen-Dürr et al., Proc Natl Acad Sci U S A 1993
:
Activation of
cyclin A expression by
MYC led to a growth factor independent association of cyclin A and cdk2 with the transcription factor E2F and correlated with an increase in E2F transcriptional activity
Pérez-Roger et al., Oncogene 1997
:
Myc activation of cyclin E/Cdk2 kinase
involves induction of
cyclin E gene transcription and inhibition of p27 ( Kip1 ) binding to newly formed complexes
Berns et al., Oncogene 1997
:
Repression of
c-Myc responsive genes in cycling cells
causes G1 arrest through reduction of
cyclin E/CDK2 kinase activity
Müller et al., Oncogene 1997
:
Activation of
Myc triggers a rapid induction of
cyclin E/cdk2 kinase activity and degradation of p27