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NOTCH1 — PCNA

Text-mined interactions from Literome

Sarmento et al., J Exp Med 2005 : Cyclin dependent kinase inhibitors ( CKIs ) and Notch receptor activation have been shown to influence adult stem cells and progenitors by altering stem cell self-renewal and proliferation
Carlson et al., Nature 2008 : Importantly, endogenous Notch and pSmad3 antagonize each other in the control of satellite-cell proliferation, such that activation of Notch blocks the TGF-beta dependent upregulation of the cyclin dependent kinase (CDK) inhibitors p15, p16, p21 and p27, whereas inhibition of Notch induces them
Ma et al., Cell Prolif 2009 : During injury recovery, disruption of Notch signalling by treatment with the gamma-secretase inhibitor reduced expression of ABCG2 and PCNA, but promoted expression of CK19, while persistent activation of Notch signalling promoted expression of ABCG2 and PCNA , but reduced expression of CK19