Gene interactions and pathways from curated databases and text-mining

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PDC — TNF

Text-mined interactions from Literome

Dolganiuc et al., J Immunol 2006 (Hepatitis C, Chronic...) : We identified CD14+ monocytes as the source of TNF-alpha and IL-10 in the HCV core induced inhibition of PDC IFN-alpha production
Takeda et al., Arterioscler Thromb Vasc Biol 2009 : Northern blot analysis and ELISA revealed that LPS induced TNF-alpha upregulation was strongly suppressed by PHD inhibitors, dimethyloxallyl glycine ( DMOG ), and TM6008 in RAW264.7 macrophages
Chehimi et al., J Virol 2010 (HIV Infections...) : The function of plasmacytoid dendritic cells (PDC) in chronic human immunodeficiency virus type 1 ( HIV-1 ) infection remains controversial with regard to its potential for sustained alpha interferon ( IFN-alpha ) production and induction of PDC dependent tumor necrosis factor (TNF) related apoptosis inducing ligand ( TRAIL ) -mediated cytotoxicity of HIV infected cells