Gene interactions and pathways from curated databases and text-mining

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MAP2K6 — PDHB

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: PDHB → MAP2K6 (decreases, PDHB Activity)
    Evidence: to characterize changes in levels of proteins in MKK6 transgenic mouse hearts, focusing on proteins in mitochondria, which play key roles in mediating I/R injury in the heart. Of the 386 mitochondrial proteins identified, the levels of 58 were decreased, while only 2 were increased in the MKK6 transgenic mouse hearts