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GNRH1 — PET100

Text-mined interactions from Literome

Zheng et al., Endocrinology 1994 : However, the ability of GnRH to stimulate phosphatidylethanol ( PEt ) in the presence of ethanol suggested that phospholipase-D may also participate in DG formation
Poulin et al., Mol Cell Endocrinol 1996 : BAY-K8644 a VSCC agonist significantly potentiated, while the VSCC antagonist nitrendipine markedly inhibited GnRH induced AA release and PEt production ... The GnRH induced PEt formation was markedly diminished in PKC depleted cells or after PKC inhibition
Zheng et al., Proc Natl Acad Sci U S A 1997 (Ion Channel Gating) : GnRH induced PEt production was reduced by inhibition of phospholipase C-dependent phosphoinositide hydrolysis by U73122 and neomycin, suggesting that signaling from phospholipase C led to activation of PLD ... The intermediate role of protein kinase C ( PKC ) in this process was indicated by the ability of phorbol 12-myristate 13-acetate to induce time- and dose dependent increases in PEt and diacylglycerol, but not inositol trisphosphate, and by reduction of GnRH induced PEt accumulation in PKC depleted cells
Poulin et al., Mol Cell Endocrinol 1998 : In spite of the presence of PKC inhibitors or down-regulation of PKC isoforms by TPA, the desensitizing effect of the neuropeptide on GnRH induced IPs, AA and PEt formation remained unchanged