◀ Back to IRF6

IRF6 — PGC

Text-mined interactions from Literome

Puigserver et al., Mol Cell 2001 (Cachexia) : Cytokine or lipopolysaccharide (LPS) induced activation of PGC-1 in cultured muscle cells or muscle in vivo causes increased respiration and expression of genes linked to mitochondrial uncoupling and energy expenditure
Feingold et al., Am J Physiol Endocrinol Metab 2004 (Acute-Phase Reaction) : The decrease in expression of RXRalpha, -beta, and -gamma, PPARalpha and -delta, and TRalpha and -beta, and of the coactivators CBP/p300, SRC-1, SRC-3, TRAP220, and PGC-1 and the genes they regulate, induced by LPS in the heart, could account for the decreased expression of key proteins required for fatty acid oxidation and thereby play an important role in cardiac contractility
Planavila et al., Biochim Biophys Acta 2005 : LPS-stimulation of H9c2 cardiac cells also led to a 30 % reduction ( P < 0.05 ) in the mRNA levels of PPARgamma Coactivator 1 (PGC-1) that was consistent with the reduction in the protein levels of this coactivator ... Co-immunoprecipitation studies showed that LPS-stimulation led to a reduction in the physical interaction between PGC-1 and PPARbeta/delta and that this reduction was prevented in the presence of atorvastatin