Fernández-Tome et al., Biochem Biophys Res Commun 2004
:
Our results indicate that PGD ( 2 ) stimulatory effect involves both PLD and ERK1/2-MAPK activation, and both pathways operate independently of PC synthesis homeostasis
Imamura et al., Cell Signal 1995
:
These results strongly suggest that PGD2 activates phospholipase D in a Ca2+/calmodulin dependent manner in osteoblast-like cells, and that protein kinase C is not essential for the PGD2 induced activation of phospholipase D