Zenhom et al., Immunobiology 2011
(Inflammation) :
PGlyRP3 gene expression was induced by PPAR? ligands including GW1929 and some FFA ... In conclusion, PPAR? mediates a modulation of PGlyRP3 gene expression, which is involved in inhibiting inflammation through negative regulation of NF-?B pathway
Zenhom et al., J Nutr 2011
:
Antagonizing PPAR? by culturing the cells with GW9662 for 24 h inhibited the oligosaccharide induced PGlyRP3 production and the antiinflammatory effect of the oligosaccharides