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PIM1 — RELA
Text-mined interactions from Literome
Jones et al., J Leukoc Biol 2001
(MAP Kinase Signaling System) :
Stimulation of RAW 264.7 macrophages by LPS, LAM, STF, and
PIM rapidly
activated nuclear factor (NF)-kappaB , activator protein-1 (AP-1), and mitogen activated protein ( MAP ) kinases
Yan et al., Braz J Med Biol Res 2006
:
In this study, we found that
Pim-1 inhibited the Elk-1 and
NFkappaB transcriptional activities induced by activation of the mitogen activated protein kinase cascade in reporter gene assays ... These data indicate that
Pim-1 does not
regulate the activation of Erk1/2, Elk-1 or
NFkappaB
Zemskova et al., J Biol Chem 2008
(Prostatic Neoplasms) :
PIM1 in turn mediates docetaxel
induced activation of
NFkappaB transcriptional activity, and PIM1 depends in part on RELA/p65 proteins for its prosurvival effects
Doz et al., J Biol Chem 2009
(Tuberculosis) :
PIM inhibited LPS/TLR4 induced
NFkappaB translocation
Nihira et al., Cell Death Differ 2010
:
Pim-1 controls
NF-kappaB signalling by stabilizing RelA/p65