Gene interactions and pathways from curated databases and text-mining

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PIM1 — RELA

Text-mined interactions from Literome

Jones et al., J Leukoc Biol 2001 (MAP Kinase Signaling System) : Stimulation of RAW 264.7 macrophages by LPS, LAM, STF, and PIM rapidly activated nuclear factor (NF)-kappaB , activator protein-1 (AP-1), and mitogen activated protein ( MAP ) kinases
Yan et al., Braz J Med Biol Res 2006 : In this study, we found that Pim-1 inhibited the Elk-1 and NFkappaB transcriptional activities induced by activation of the mitogen activated protein kinase cascade in reporter gene assays ... These data indicate that Pim-1 does not regulate the activation of Erk1/2, Elk-1 or NFkappaB
Zemskova et al., J Biol Chem 2008 (Prostatic Neoplasms) : PIM1 in turn mediates docetaxel induced activation of NFkappaB transcriptional activity, and PIM1 depends in part on RELA/p65 proteins for its prosurvival effects
Doz et al., J Biol Chem 2009 (Tuberculosis) : PIM inhibited LPS/TLR4 induced NFkappaB translocation
Nihira et al., Cell Death Differ 2010 : Pim-1 controls NF-kappaB signalling by stabilizing RelA/p65