Gene interactions and pathways from curated databases and text-mining

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MAP2K7 — PLA2G4A

Text-mined interactions from Literome

Beck-Speier et al., Free Radic Biol Med 2005 : Particle induced formation of AA metabolites and ROS was dependent on mitogen activated protein kinase kinase 1 activation of cytosolic phospholipase A2 (cPLA2) as shown by inhibitor studies
van der Merwe et al., J Pharmacol Exp Ther 2009 : Immunoblot analysis showed a PAR(2) induced increase in cPLA(2) phosphorylation that was blocked by the mitogen activated protein kinase kinase inhibitor, PD98059 [ 2- ( 2-amino-3methoxyphenyl ) -4H-1benzopyran-4-one, C ( 16 ) H ( 13 ) NO ( 3 ) ], and the pan-protein kinase C inhibitor, GFX ( bisindolylmaleimide )