El-Armouche et al., Circulation 2006
(Arrhythmias, Cardiac...) :
In cAF, the ratio of Thr-35 phosphorylated to total I-1 was 10-fold higher, which suggests that the enhanced phosphorylation of phospholamban may result from a stronger PP1 inhibition by PKA hyperphosphorylated ( activated ) I-1
Wu et al., Journal of translational medicine 2012
(Heart Defects, Congenital) :
Increased PP1 could result in the decreased PLN-Ser16 and inhibition of PP1 is a potential therapeutic target for heart dysfunction in pediatrics