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CSF2 — PRG2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Quintero et al., J Rheumatol 2001
:
Granulocyte-macrophage
colony stimulating factor activates
proteoglycan , type II collagen, and cAMP production by rat articular chondrocytes through specific binding sites ... To evaluate the
effects of granulocyte-macrophage
colony stimulating factor ( GM-CSF ) on rat articular chondrocyte ( AC ) with respect to DNA synthesis, collagen type II and
proteoglycan ( PG ) synthesis and expression, and cAMP production ; to examine these cells for the presence of GM-CSF-specific binding sites ; and to study their regulation by growth factors and cytokines
Quintero et al., Cytokine 2008
:
GM-CSF strongly stimulates, and IL-1beta
inhibits ,
proteoglycan and collagen synthesis