Gene interactions and pathways from curated databases and text-mining

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PSMA7 — PSMD3

Pathways - manually collected, often from reviews:

  • BioCarta proteasome complex: 26S Proteasome complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1-PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7) → None (degradation, activates)
  • BioCarta proteasome complex: 26S Proteasome complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1-PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7) (degradation, activates)
  • BioCarta proteasome complex: PA700 Activator complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1) → 26S Proteasome complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1-PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7) (modification, collaborate)
  • BioCarta proteasome complex: PA700 Activator complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1) → 20S Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2) (modification, collaborate)
  • BioCarta proteasome complex: 26S Proteasome complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1-PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7) → 20S Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2) (modification, collaborate)
  • BioCarta proteasome complex: PA700 Activator complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1) → 20S Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2) (modification, collaborate)
  • BioCarta proteasome complex: PA700 Activator complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1) → Hybrid Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMD3-PSMD12-PSMD11-PSMA2-PSMD14-RPN1-RPN2-PSMD4-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2) (modification, collaborate)
  • BioCarta proteasome complex: 20S Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2) → Hybrid Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMD3-PSMD12-PSMD11-PSMA2-PSMD14-RPN1-RPN2-PSMD4-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2) (modification, collaborate)
  • Reactome Reaction: PSMA7 → PSMD3 (direct_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Husom et al., Arch Biochem Biophys 2004 (Atrophy) : These results suggest significant alterations in the intrinsic activity, the percentage of immunoproteasome, and the regulation of the 20S proteasome by PA28 and PA700 in aged muscle
Thompson et al., J Biol Chem 2009 : Subcomplexes of PA700 , the 19 S regulator of the 26 S proteasome , reveal relative roles of AAA subunits in 26 S proteasome assembly and activation and ATPase activity