Gene interactions and pathways from curated databases and text-mining

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CAPN1 — PTEN

Text-mined interactions from Literome

Kulkarni et al., Oncogene 2010 (Breast Neoplasms) : Together, by regulating the activation of HER2 and PTEN/AKT1 , calpain regulates trastuzumab sensitivity and survival, and the deregulation of the activation of calpain promotes trastuzumab resistance
Briz et al., J Neurosci 2013 : Calpain-2, but not calpain-1 , treatment of brain homogenates resulted in PTEN degradation