Gene interactions and pathways from curated databases and text-mining

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CASP14 — PTEN

Text-mined interactions from Literome

Huang et al., Arterioscler Thromb Vasc Biol 2002 : Moreover, PTEN overexpression induced cleavage of caspase-3 and significantly increased apoptosis compared with control cells
Selvendiran et al., J Pharmacol Exp Ther 2009 (Coronary Restenosis) : Conversely, overexpression of PTEN by cDNA transfection activated caspase-3 and increased apoptosis
Glass et al., Am J Physiol Heart Circ Physiol 2011 (Disease Models, Animal...) : Assessment of apoptosis revealed that overexpression of miR-1 in transplanted ES cells protected host myocardium from MI-induced apoptosis through activation of p-AKT and inhibition of caspase-3 , phosphatase and tensin homolog , and superoxide production