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CSF1 — PTPN11
Text-mined interactions from Literome
Jack et al., Blood 2009
(MAP Kinase Signaling System) :
SHP2 inhibition
reduced ERK activation in G-CSF, but not
M-CSF , and reduced colony forming unit-granulocytes, underscoring divergent pathways to ERK activation
Zhang et al., Blood 2011
(MAP Kinase Signaling System) :
We previously found that G-CSF induces SHP2 tyrosine phosphorylation and that chemical inhibition of
SHP1/SHP2 reduces CFU-G and
prevents G-CSF but not
M-CSF activation of ERK