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FOS — RAC1

Text-mined interactions from Literome

Wroblewski et al., J Cell Sci 2003 (Neoplasm Invasiveness) : RhoA acted through activation of both NF-kappaB and AP-1, whereas Rac activated NF-kappaB but not AP-1
Sakoda et al., J Dent Res 2006 : Dominant negative Rac1 severely inhibited interleukin-1alpha induced NF-kappaB and AP-1 promoter activity
Lee et al., Oncogene 2009 : In summary, Galpha(12) and Galpha(13) regulate the expression of the TGFbeta1 gene through an increase in Rho/Rac dependent AP-1 activity, implying that the G-protein coupled receptor ( GPCR ) -Galpha(12) pathway is involved in the TGFbeta1 mediated transdifferentiation process
Nishita et al., Mol Cell Biol 2010 : We further show that polymerized Dvl is colocalized with Rac1 and that suppressed expression of Rac1 inhibits Wnt5a induced AP-1 activation
Venkatesan et al., J Mol Cell Cardiol 2010 : EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1 dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling
Collins et al., J Biol Chem 1996 : In 1321N1 cells, where thrombin stimulates G12 dependent mitogenesis, coexpression of N17Rac1 or a dominant negative mutant of MEKK1 ( MEKKDelta ( K432M ) ) inhibits c-Jun/AP-1 sensitive reporter gene expression stimulated by thrombin or Galpha12
Malliri et al., J Cell Biol 1998 : Our data establish a novel link between AP-1 activity and EGFR activation of Rac and Rho, which in turn mediate the actin cytoskeletal rearrangements required for cell motility and invasion