Gene interactions and pathways from curated databases and text-mining

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ABL1 — RAC2

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Sini et al., Nat Cell Biol 2004 : Genetic or pharmacological interference with Abl ( and the related kinase Arg ) resulted in a marked decrease in Rac activation induced by physiological doses of growth factors
Sirvent et al., Oncogene 2007 (Breast Neoplasms...) : In contrast, Abl controls the activation of the small GTPase Rac for oncogenic signalling and active Rac partly rescued Src transformation in cells with inactive Abl
Jin et al., Mol Biol Cell 2007 : The Abl dependent dorsal membrane localization of activated Rac explains its positive role in ruffling and negative role in cell spreading and migration
Skorski et al., Proc Natl Acad Sci U S A 1998 (Leukemia, Experimental...) : We show here that the small GTP binding protein Rac is activated by BCR/ABL in a tyrosine kinase dependent manner