Gene interactions and pathways from curated databases and text-mining

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CSF1 — RAF1

Text-mined interactions from Literome

Baccarini et al., EMBO J 1990 : The serine/threonine kinase RAF-1 is phosphorylated in intact macrophages in response to CSF-1 at 37 degrees C The augmented phosphorylation of RAF-1 and a concomitant increase in RAF-1 associated serine/threonine kinase activity are kinetically later events than CSF-1 induced protein tyrosine phosphorylation
Büscher et al., Mol Cell Biol 1995 : Therefore, CSF-1 and LPS target the MAPK network by two alternative pathways, both of which induce Raf-1 activation