Gene interactions and pathways from curated databases and text-mining

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IL1A — REL

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Inadera et al., Endocrinology 2000 : The IL-1alpha induced p50/c-Rel complex to the A2 probe was also, to a lesser extent, decreased by E2 or XE treatment
Gringhuis et al., PLoS Pathog 2011 : Here we demonstrate that Malt1 recruitment is pivotal to T ( H ) -17 immunity by selective activation of NF-?B subunit c-Rel , which induces expression of T ( H ) -17 polarizing cytokines IL-1ß and IL-23p19
Nedjai et al., Cell Immunol 2011 (Hereditary Autoinflammatory Diseases) : Interestingly, high p65 activity was associated with elevated IL-8 secretion, whereas high c-Rel activity increased IL-1ß and IL-12 secretion