Schaffer et al., J Immunol 1999
:
Electrophoretic mobility shift assays showed that p50/p65/c-Rel and STAT-6 are effectively induced by CD40L and IL-4 , respectively, and bind to specific DNA motifs within the ECS
Grumont et al., J Exp Med 2001
:
c-Rel regulates interleukin 12 p70 expression in CD8 ( + ) dendritic cells by specifically inducing p35 gene transcription
Temmerman et al., Blood 2006
(Ectodermal Dysplasia...) :
As a consequence, CD40 stimulated EDI DCs failed to synthesize the c-Rel dependent cytokine interleukin-12 , had impaired up-regulation of costimulatory molecules, and failed to support allogeneic lymphocyte proliferation in vitro