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CCND1 — RENBP
Text-mined interactions from Literome
Guh et al., Am J Kidney Dis 2001
:
We found that
AGE increased
cyclin D1 expression and cyclin dependent kinase (cdk)4 activity while decreasing p21 ( WAF1/CIP1 ) expression ... In addition, STAT5 decoy ODN reversed
AGE induced cell-cycle
dependent cellular proliferation and
cyclin D1 protein expression
Chen et al., Translational research : the journal of laboratory and clinical medicine 2007
:
AGE also
increased tyrosine phosphorylation of Hsp70, cyclin E, and
cyclin D1 ( to a lesser extent ) while increasing Hsp70 protein interactions with STAT1, STAT3, STAT5b, cyclin D1, and cyclin E. AGE induced tyrosine phosphorylation of Hsp70 and cyclin E ( but not cyclin D1 ) was attenuated by AG-490 ...
AGE induced mitogenesis,
cyclin D1 , and cyclin E were attenuated by Hsp70 antisense oligodeoxynucleotide and 2-aminopurine ( an Hsp70 inhibitor )