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BMP7 — RGMA
Text-mined interactions from Literome
Babitt et al., J Biol Chem 2005
:
We show that
RGMa enhances
BMP , but not TGF-beta, signals in a ligand dependent manner in cell culture ...
RGMa mediates
BMP signaling through the classical BMP signaling pathway involving Smad1, 5, and 8, and it up-regulates endogenous inhibitor of differentiation ( Id1 ) protein, an important downstream target of BMP signals
Xia et al., J Biol Chem 2007
:
Furthermore, in BmpRII-null pulmonary artery smooth muscle cells, BMP2 and BMP4 signaling was reduced by inhibition of endogenous
RGMa expression, and RGMa mediated
BMP signaling
required ActRIIA expression
Halbrooks et al., Journal of molecular signaling 2007
:
Here, we investigate whether
RGMa , RGMb, and RGMc
play required roles in
BMP and TGFbeta signaling in the mouse myoblast C2C12 cell line