Gao et al., J Biol Chem 2005
:
Expression of exogenous Vav1 demonstrates that Y160F, but not wild type or the Vav1Y174F mutant, inhibits Rac and Rho activation during alpha ( v ) beta ( 3 ) -mediated cell adhesion to vitronectin
Bartolomé et al., Cancer Res 2006
(Melanoma...) :
Blocking Vav expression by RNA interference results in impaired activation of Rac and Rho by CXCL12 and in a remarkable inhibition of CXCL12 promoted invasion
Olson et al., Curr Biol 1996
:
FGD1 activates Cdc42, whereas Vav activates Rho , Rac and Cdc42