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PPARG — SIRT2

Text-mined interactions from Literome

Das et al., Prostaglandins Leukot Essent Fatty Acids 2005 (Diabetes Mellitus, Type 2...) : In addition, SIRT1 repressed PPAR-gamma , and overexpression of SIRT1 attenuated adipogenesis, and upregulation of SIRT in differentiated fat cells triggered lipolysis and loss of fat, events that are known to attenuate insulin resistance and prolong life span
Zhang et al., J Bone Miner Res 2010 (Bone Diseases, Metabolic) : In contrast, adipocyte formation and Ppar-gamma expression in cultures were increased, and expression of the polycomb protein sirtuin ( Sirt1 ) was reduced