Habib et al., Biochemistry 2002
:
Retroviral mediated transduction of wild-type gamma c into XSCID JT cells restored function to the IL-21R, as shown by IL-21 induced tyrosine phosphorylation of JAK1 and JAK3, and downstream activation of STAT5 , in JT/gamma c cells as well as BaF3/IL-21R alpha and primary splenic B cells
Furuhata et al., Biochem Biophys Res Commun 2009
:
Like JAK2V617F overexpression, constitutively active STAT5 or STAT3 induced aberrant p27 ( Kip1 ) expression of Ba/F3 cells