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MAPK6 — SMC2

Text-mined interactions from Literome

Khan et al., J Biol Chem 2004 (MAP Kinase Signaling System) : Here we demonstrate that macrophage engagement of SMC-ECM triggers PKC dependent activation of MAPK ( erk1/2 ) leading to increased expression of cyclooxygenase (COX)-2 and prostaglandin ( PG ) E ( 2 ) synthesis
Hu et al., Heart Lung Circ 2002 : Suramin inhibited SMC migration and proliferation in vivo and in vitro by blocking platelet derived growth factor ( PDGF ) -initiated PDGF receptor activation and MAPK-AP-1 signalling, and was also effective in inhibition of neointima hyperplasia in mouse vein bypass grafts
Butoi et al., Biochim Biophys Acta 2011 : Monocyte-SMC interaction induced the phosphorylation of p38MAPK and activation of AP-1 transcription factor
Nelson et al., J Vasc Surg 1998 : MAPK activity is essential for both SMC migration and proliferation, and distinct phases of enzyme activation are required to stimulate these two discrete cellular events