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CASP3 — SOD2

Text-mined interactions from Literome

Noshita et al., J Cereb Blood Flow Metab 2001 (Ischemic Attack, Transient) : The current study revealed Mn-SOD might affect cytochrome c translocation and downstream caspase activation in the mitochondrial dependent cell death pathway after transient FCI
Kim et al., Exp Mol Med 2003 : Furthermore, SOZ and IOZ induced the cleavage of procasapase-3 ( 35 kDa ) to give rise to an active caspase-3 ( 20 kDa ), which was blocked by Tat- SOD but not by 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide ( PTIO ), a scavenger of NO
Sakudo et al., Biochem Biophys Res Commun 2003 : Re-introduction of Prnp rescued cells from apoptosis, upregulated superoxide dismutase ( SOD ) activity, enhanced superoxide anion elimination, and inhibited caspase-3/9 activation
Yoshida et al., Lab Invest 2003 : Accordingly, neither superoxide dismutase nor N ( G ) -monomethyl-L-arginine had significant effects on HRPE cell apoptosis or caspase-3 activation
Elner et al., Trans Am Ophthalmol Soc 2003 : Accordingly, neither SOD nor NO inhibitors had significant effects on HRPE cell apoptosis or caspase-3 activation
Conde de la Rosa et al., J Hepatol 2006 (MAP Kinase Signaling System...) : ( 3 ) PEG-SOD prevents ERK1/2-, JNK- phosphorylation, caspase activation and apoptosis induced by menadione
Vincent et al., Exp Neurol 2007 (Diabetes Mellitus...) : We demonstrate that overexpression of SOD2 decreases superoxide ( O ( 2 ) ( - ) ) in cultured primary dorsal root ganglion ( DRG ) neurons and subsequently blocks caspase-3 activation and cellular injury
García-Berrocal et al., J Laryngol Otol 2010 (Disease Models, Animal) : Inhibition of caspase-3 activity significantly reduced cochlear heat shock protein 70 expression and total superoxide dismutase activity, and improved auditory brainstem response and auditory steady state response thresholds
Wang et al., J Biol Chem 2011 (Disease Models, Animal...) : By contrast, ectopic Drosophila Sod2 expression and antioxidant treatment reduced ROS and caspase 3 activity and extended the life span of the SCA12 fly model
Yang et al., Int Immunopharmacol 2013 (Disease Models, Animal...) : XN significantly decreased malondialdehyde, potentiated superoxide dismutase and glutathione peroxidase, reduced Bax expression, promoted Bcl-xL and inhibited caspase 3 activity in liver tissues compared with the animals without XN intervention