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NOX4 — SOD2

Text-mined interactions from Literome

Takenaga et al., Free Radic Biol Med 1999 (Lung Neoplasms) : It was also found that PC-SOD prevented a decrease of pulmonary NOx level following tumor cell inoculation
Alvarez-Maqueda et al., Atherosclerosis 2004 : We show that Hcy increased superoxide anion ( O2*- ) release by neutrophils to the extracellular medium, and that this effect was inhibited by superoxide dismutase and diphenyleneiodonium ( DPI ), an inhibitor of NADPH oxidase activity
Tamaoki et al., Am J Physiol Lung Cell Mol Physiol 2004 (MAP Kinase Signaling System) : This effect was attenuated by Cu- and Zn-containing superoxide dismutase ( Cu/Zn SOD ) and apocynin, an inhibitor of NADPH oxidase , and completely inhibited by pretreatment with the epidermal growth factor receptor (EGF-R) tyrosine kinase inhibitors AG-1478 and BIBX-1382, and the mitogen activated protein kinase kinase inhibitor PD-98059
Walch et al., Atherosclerosis 2006 (Atherosclerosis) : Incubation of HUVECs with IL-4 resulted in an increased production of reactive oxygen species and extracellular O ( 2 ) ( - ) ( * ) measured using fluorogenic probes and Cytochrome c that was inhibited by superoxide dismutase or gp91ds-tat, a selective NADPH oxidase inhibitor
Bayraktutan et al., Free Radic Biol Med 2005 : Suppression of O ( 2 ) ( - ) availability by a cell-permeable superoxide dismutase mimetic or inhibition of NAD ( P ) H oxidase activity via its specific inhibitors ( apocynin, diphenyleneiodinium, phenylarsine oxide, and 4- ( 2-aminoethyl ) bezenesulfonyl fluoride ) or antisense p22-phox cDNA attenuated cell growth independent of changes in intracellular antioxidant glutathione levels
Shukla et al., Eur J Pharmacol 2006 (Hyperhomocysteinemia) : In hyperhomocysteinaemic rabbits there was a marked reduction of acetylcholine stimulated relaxation and an increase in superoxide formation that were both inhibited with superoxide dismutase and apocynin, an NADPH oxidase inhibitor
Tajima et al., Eur J Pharmacol 2008 : Nicorandil did not increase the anti-aggregation activity of endothelial NO when endothelial cells were pre treated with superoxide dismutase or 4- ( 2-aminophenyl ) -benzenesulfonyl fluoride, an inhibitor of NADPH oxidase
Kumagai et al., Atherosclerosis 2008 (Atherosclerosis) : Efrapeptin, an inhibitor of ATPase, attenuated CF6 induced suppression of PECAM-1 gene expression by blockade of acidification, whereas superoxide dismutase or apocinin, an inhibitor of NADPH oxidase , blocked AngII induced suppression of PECAM-1
Chen et al., Cardiovasc Res 2009 (MAP Kinase Signaling System) : Superoxide anion production was significantly increased due to the inhibition of mitochondrial membrane potential and catalase and superoxide dismutase ( SOD ) activities as well as activation of NADPH oxidase
Fujita et al., Hypertens Res 2012 (Diabetes Mellitus...) : Finally, treatment of C57BL/6-Akita mice with apocynin, an NAD ( P ) H oxidase inhibitor, also increased the renal protein expression of SOD and Nrf2. Collectively, our data suggest that NAD ( P ) H oxidase negatively regulates renal SOD , possibly by downregulation of Nrf2, and that telmisartan could upregulate renal SOD by the suppression of NAD ( P ) H oxidase and subsequent upregulation of Nrf2, leading to the amelioration of renal oxidative stress and diabetic renal changes
Santiago et al., Free Radic Biol Med 2013 : H2O2 ( 50µM ) increased by about 10-fold basal superoxide anion ( O2 ( - ) ) production in coronary arteries measured by lucigenin enhanced chemiluminescence, and H2O2 elicited contractions were reduced by the superoxide dismutase mimetic tempol and by NADPH oxidase inhibition
Polla et al., Inflammation 1995 : With respect to functional effects of HS, we examined, in human monocytes and in neutrophils, the effect of HS on NADPH oxidase mediated O2- generation as well as on phagocytosis, bacterial killing, and superoxide dismutase ( SOD ) activity
Patriarca et al., Mol Cell Biochem 1976 : Redogenic substances, such as ascorbate or hydroquinone, and superoxide dismutase , which are known to inhibit peroxidase catalyzed reactions, also inhibited the NADPH oxidase activity of granules