Gene interactions and pathways from curated databases and text-mining

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ESR1 — SPP1

Text-mined interactions from Literome

Vanacker et al., EMBO J 1999 : Accordingly, the osteopontin gene promoter is stimulated through SFRE sequences, by ERRalpha as well as by ERalpha , but not by ERbeta
de Silva Rudland et al., Clin Cancer Res 2006 (Breast Neoplasms...) : It is suggested that in human breast cancer, S100A4 exerts some of its effects through angiogenesis, and that osteopontin is dependent on ERalpha for its expression
Zirngibl et al., J Cell Biochem 2013 : Divergent regulation of the Osteopontin promoter by the estrogen receptor related receptors is isoform- and cell context dependent