Gene interactions and pathways from curated databases and text-mining

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SPP1 — TCF15

Text-mined interactions from Literome

Shinohara et al., Nat Immunol 2006 : The observation that the T-bet transcription factor allows tissue-specific upregulation of intracellular osteopontin (Opn-i) in plasmacytoid dendritic cells ( pDCs ) suggests that Opn might contribute to the expression of interferon-alpha ( IFN-alpha ) in those cells
Abe et al., Hypertens Res 2008 : In conclusion, these data suggest that Ang II-induced OPN expression in VSMC is mediated by signaling cascades involving G ( q/11 ) the Ras-ERK axis, and the Src kinase family, and by the transcription factor , Ets-1
Sharma et al., Molecular cancer 2010 : In this paper, we for the first time report that TSA suppresses PMA induced OPN gene expression in human cervical carcinoma cells and previously unidentified AP-1 transcription factor is involved in this event
Chen et al., J Exp Clin Cancer Res 2010 (Carcinoma, Hepatocellular...) : The effects of one selected transcription factor on OPN expression were further evaluated
Flajollet et al., Mol Cancer Res 2011 (Neoplasm Metastasis...) : Abnormal expression of the ERG transcription factor in prostate cancer cells activates osteopontin