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HDAC1 — SUDS3
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
HDAC1
—
SUDS3
(physical association, affinity chromatography technology)
Joshi et al., Molecular systems biology 2013
-
IRef Biogrid Interaction:
HDAC1
—
SUDS3
(physical association, affinity chromatography technology)
Fleischer et al., Mol Cell Biol 2003
-
IRef Biogrid Interaction:
HDAC1
—
SUDS3
(physical association, affinity chromatography technology)
Alland et al., Mol Cell Biol 2002
-
MIPS CORUM HCF-1 complex:
HCF-1 complex complex (ASH2L-HCFC1-HDAC1-HDAC2-HSPA4-HSPA5-HSPA8-OGT-RBBP4-RBBP7-SAP30-SETD1A-SIN3A-SIN3B-SP1-SUDS3-WDR5-HSP90AA1-HSP90AB1)
Wysocka et al., Genes Dev 2003
-
MIPS CORUM ING2 complex:
ING2 complex complex (ARID4A-BRMS1-BRMS1L-HDAC1-HDAC2-ING2-RBBP4-RBBP7-SAP130-SAP30-SIN3A-SUDS3)
Doyon et al., Mol Cell 2006
-
MIPS CORUM SAP complex (Sin3-associated protein complex):
SAP complex (Sin3-associated protein complex) complex (ARID4B-HDAC1-HDAC2-RBBP4-RBBP7-SAP130-SAP30-SIN3A-SUDS3)
Fleischer et al., Mol Cell Biol 2003
-
MIPS CORUM SIN3-SAP25 complex:
SIN3-SAP25 complex complex (ARID4B-HDAC1-HDAC2-RBBP4-RBBP7-SAP130-SAP18-SAP30-SIN3A-SUDS3)
Shiio et al., Mol Cell Biol 2006
-
MIPS CORUM SIN3-SAP25 complex:
SIN3-SAP25 complex complex (ARID4B-HDAC1-HDAC2-RBBP4-RBBP7-SAP130-SAP18-SAP30-SIN3A-SUDS3)
Shiio et al., Mol Cell Biol 2006
-
IRef Corum Interaction:
Complex of 21 proteins
(association, anti tag coimmunoprecipitation)
Shiio et al., Mol Cell Biol 2006
-
IRef Corum Interaction:
Complex of 28 proteins
(association, anti bait coimmunoprecipitation)
Fleischer et al., Mol Cell Biol 2003
-
IRef Corum Interaction:
Complex of 25 proteins
(association, mass spectrometry studies of complexes)
Doyon et al., Mol Cell 2006
-
IRef Corum Interaction:
Complex of 20 proteins
(association, anti tag coimmunoprecipitation)
Wysocka et al., Genes Dev 2003
-
IRef Hprd Interaction:
Complex of 17 proteins
(in vivo)
Alland et al., Mol Cell Biol 2002
-
IRef Hprd Interaction:
HDAC1
—
SUDS3
(in vivo)
Alland et al., Mol Cell Biol 2002
-
IRef Intact Interaction:
Complex of 92 proteins
(association, anti tag coimmunoprecipitation)
Joshi et al., Molecular systems biology 2013
-
IRef Intact Interaction:
Complex of 47 proteins
(association, anti tag coimmunoprecipitation)
Joshi et al., Molecular systems biology 2013
-
IRef Intact Interaction:
Complex of SIN3A-SAP130-RBBP7-SUDS3-HDAC2-HDAC1-SAP30-ARID4B
(association, anti tag coimmunoprecipitation)
Williams et al., Nature 2011
-
IRef Intact Interaction:
Complex of 14 proteins
(association, anti tag coimmunoprecipitation)
Wysocka et al., Genes Dev 2003
Text-mined interactions from Literome
Bocheński et al., J Physiol Pharmacol 1999
:
Pretreatment with a PAF receptor antagonist ; WEB 2170 ( 5 and 25 mg/kg ) inhibited both PAP and SAP responses to LPS ( 4 mg/kg/min ) while an inhibitor of thromboxane synthesis ; Camonagrel ( 10 and 20 mg/kg ) abolished PAP response without a major effect on
SAP response to
LPS
Chacon-Cruz et al., Pediatr Res 2000
:
PS+SAP also
inhibited the formyl peptide induced [
Ca2+ ] response of neutrophils ( p < 0.01 ), but only in the presence of external Ca2+
Paul et al., J Biol Chem 2000
(MAP Kinase Signaling System) :
Acute phorbol 12-myristate 13-acetate pretreatment also inhibited
TNFalpha stimulated
SAP kinase activity, while chronic pretreatment reversed the effects of UTP
Ochrietor et al., Cytokine 2000
:
Role of
STAT3 and C/EBP in cytokine dependent expression of the mouse
serum amyloid P-component (SAP) and C-reactive protein (CRP) genes ...
Role of STAT3 and
C/EBP in cytokine dependent expression of the mouse
serum amyloid P-component (SAP) and C-reactive protein (CRP) genes
de Haas et al., Infect Immun 2000
:
Using HDL coated magnetic beads prebound with SAP, we demonstrated that HDL bound
SAP prevented the binding of
LPS to HDL
Hutchinson et al., Mol Med 2000
:
Gel filtration chromatography and density gradient ultracentrifugation were used to compare SAP with the closely related molecule, C-reactive protein ( CRP ; which is known to be a single pentamer ) and the
effect of human serum
albumin on
SAP autoaggregation was investigated
Singh et al., Scand J Immunol 2001
(Acute-Phase Reaction) :
Both in vivo and in vitro the maximum production of CSFs occurred 6 h after initiation of stimulation, and returned to the background levels by 48 h. Mannose 6-P, mannose 1-P and mannose, and not other sugars inhibited the SAP induced production of CSFs by macrophages which suggests that
SAP interaction with macrophages was
mediated by specific
glycoprotein-receptors ... A neutralizing ( 100 % ) concentration of rabbit antimouse interleukin (IL)-1 polyclonal antibody had no effect on the
SAP induced
CSF production, indicating that it would be IL-1 independent
Howie et al., Blood 2002
:
Molecular dissection of the signaling and costimulatory functions of CD150 ( SLAM ) :
CD150/SAP binding and
CD150 mediated
costimulation
Aoukaty et al., J Biol Chem 2002
(Lymphoproliferative Disorders) :
We report here a
role for
phosphoinositide 3-kinase (PI3K) in the recruitment and association of
SAP/SH2D1A to 2B4 in human NK cells
Chazova et al., Ter Arkh 2002
(Hypertension) :
With sufficient antihypertensive effect on
SAP , the drug did not
induce an excessive decrease of
DAP and did not affect heart rate and blood biochemistry
Mignot et al., Mol Microbiol 2002
:
More importantly,
Sap is required for the temporal control of eag, and
EA1 is
involved in strict feedback regulation of eag
Li et al., J Biol Chem 2003
(Lymphoproliferative Disorders) :
Because SAP also blocked the recruitment of SHP-2 to SLAM in these cells, we propose a dual functional
role for
SAP in
SLAM signaling by acting both as an adaptor for FynT and an inhibitor to SHP-2 binding
Bozzo et al., Eur J Biochem 2002
:
SAP1 and
SAP2 were
activated by up to 80 % by 5 mm
Mg2+ , and demonstrated potent competitive inhibition by molybdate, but mixed and competitive inhibition by Pi, respectively
Ding et al., World J Gastroenterol 2003
(Acute Disease...) :
To establish a non-traumatic, easy to induce and reproducible mouse model of
severe acute pancreatitis (SAP) induced with caerulein and
lipopolyasccharide (LPS)
Aquilina et al., Biochem J 2003
:
In the
presence of physiological levels of
Ca2+ ,
SAP was observed to exist primarily as a pentamer, reflecting its in vivo state
Kataoka et al., Cancer Res 2003
(Carcinoma, Hepatocellular...) :
ING1b and
ING2 also
repressed the
AFP promoter in Hep3B p53-null cell lines, and p53 coexpression enhanced this transcriptional repression
Boston et al., Experimental biology and medicine (Maywood, N.J.) 2004
:
We hypothesize that
PS+SAP suppresses neutrophil activation by depletion of internal Ca ( ++ ) stores and that
PS+SAP induces depletion through release of Ca ( ++ ) stores and through inhibition of Ca ( ++ ) influx
Valdez et al., J Biol Chem 2004
(Autoimmune Diseases...) :
Cross linking of
NTB-A also
induces phosphorylation of NTB-A and the association of
SAP ( SLAM associated protein ), the protein absent in X-linked lymphoproliferative disease
Vulin et al., J Biol Chem 2004
:
Finally, JNK/SAPK activity was found to increase in response to oxidants, and inhibition of
JNK/SAP blocked TBHQ increased
PAI-1-luciferase expression
Simarro et al., Int Immunol 2004
:
SAP increases FynT kinase activity and is
required for phosphorylation of
SLAM and Ly9 ...
SAP increases FynT kinase activity and is
required for phosphorylation of SLAM and
Ly9 ... Here we demonstrate that
SAP is
required for phosphorylation of both
SLAM and Ly9 in thymocytes and peripheral T cells ... Here we demonstrate that
SAP is
required for phosphorylation of both SLAM and
Ly9 in thymocytes and peripheral T cells
Taylor et al., Infect Immun 2005
(Candidiasis, Vulvovaginal) :
SAP5 expression was
induced soon after infection, whereas
SAP4 was expressed at later times and in fewer cells compared with SAP5
Veerhuis et al., Neurobiol Dis 2005
:
Also,
SAP and C1q
enhanced PrP-peptide fibril formation as revealed by electron microscopy and thioflavin S-based quantitative assays
Chuang et al., Blood 2005
(Lymphohistiocytosis, Hemophagocytic) :
Interestingly, EBV
LMP1 could transcriptionally
inhibit the expression of
SAP/SH2D1A and activate downstream molecules ERK and interferon-gamma (IFN-gamma)
Armstrong et al., J Infect Dis 2006
(Disease Models, Animal...) :
Here, we show that serum amyloid P component (SAP), a normal human plasma protein, specifically protects mice against the lethal toxicity of Stx2, both when injected into wild-type mice and when expressed transgenically ; in the
presence of human
SAP , there was greatly reduced in vivo localization of
Stx2 to the kidneys, suggesting a possible mechanism of protection
Macdonald et al., Scand J Immunol 2006
:
The
SAP-monocyte interaction was calcium independent and readily
inhibited by
C1q
Kammanadiminti et al., J Biol Chem 2006
(Colitis) :
Overexpression of wild type Hsp27 amplified the effects of SAP, whereas a phosphorylation-deficient mutant of Hsp27 abrogated
SAP induced
NF-kappaB inhibition
Chen et al., Mol Cell Biol 2006
:
SAP promotes
SLAM family receptor induced protein tyrosine phosphorylation, due to its capacity to recruit the Src related kinase FynT
Mantovani et al., Vascul Pharmacol 2006
(Cardiovascular Diseases...) :
CRP and
SAP are produced primarily in the liver in
response to
IL-6 , while PTX3 is produced by a variety of tissues and cells and in particular by innate immunity cells in response to proinflammatory signals and Toll-like receptor ( TLR ) engagement
Yasuda et al., Pancreas 2006
(Bacterial Infections...) :
These results suggest that
HMGB1 may
act as a key mediator for inflammation and organ failure in
SAP
Mauceri et al., J Neurochem 2007
:
On the contrary,
SAP97-Ser232 phosphorylation occurs within the postsynaptic compartment and is
responsible for both the disruption of
NR2A/SAP97 complex and, consequently, for NR2A insertion in the postsynaptic membrane ... On the contrary,
SAP97-Ser232 phosphorylation occurs within the postsynaptic compartment and is
responsible for both the disruption of
NR2A/SAP97 complex and, consequently, for NR2A insertion in the postsynaptic membrane
Endt et al., Eur J Immunol 2007
:
IL-2 stimulation leads to an up-regulation of
SAP expression, which can be
enhanced by
IL-12 , the stimulation of TLR3 by polyinosinic-polycytidylic acid ( poly ( I:C ) ) and to a lesser extent by IFN-alpha ...
IL-2 stimulation
leads to an up-regulation of
SAP expression, which can be enhanced by IL-12, the stimulation of TLR3 by polyinosinic-polycytidylic acid ( poly ( I:C ) ) and to a lesser extent by IFN-alpha
McCausland et al., J Immunol 2007
:
SAP regulation of follicular helper CD4 T cell development and humoral immunity is
independent of
SLAM and Fyn kinase
Kammanadiminti et al., Infect Immun 2007
:
Moreover, inhibiting the classical pathway of NF-kappaB activation did not affect
SAP induced
MCP-1 expression ... Instead, we find that
SAP induced
MCP-1 expression is dependent on posttranslational modification of the NFkappaB p65 subunit
Villar et al., Infect Immun 2007
(Candidiasis, Oral) :
Mucosal tissue invasion by Candida albicans is associated with
E-cadherin degradation,
mediated by transcription factor Rim101p and protease
Sap5p
Nakajima et al., Pancreas 2007
(Acute Disease...) :
Apoptosis of ileal mucosa was accelerated in
SAP , and
VEGF significantly
reduced the apoptosis ... Microvessel counts were significantly reduced in
SAP , and
VEGF significantly
increased them
Pisalyaput et al., J Neurochem 2008
:
Interestingly,
SAP did not
induce caspase and
calpain activation, suggesting that C1q neuroprotection is in distinct from caspase and calpain pathways ... Interestingly,
SAP did not
induce caspase and calpain activation, suggesting that C1q neuroprotection is in distinct from caspase and calpain pathways
Li et al., Immunity 2007
:
Furthermore,
SAP was
critical for
IL-4 production by T-CD4 T cells, but the PKCtheta deficiency did not alter the ability of T-CD4 T cells to produce cytokines
el-Kashef et al., Pulm Pharmacol 1991
:
Atropine or secoverine ( SEC ) inhibited equally the PVR and
SAP responses to
ACh
Zhang et al., Cancer Lett 2008
(Carcinoma, Hepatocellular...) :
Researches have shown that
ING2 can
activate p53 and p53 mediated apoptotic pathway involved in the hepatocarcinogenesis
Furukawa et al., Jpn J Pharmacol 1991
:
Before atropine, topical application of hexamethonium at the locus for stimulation of intracardiac parasympathetic nerves to the SA ( SAP stimulation ) or AV nodal region ( AVP stimulation ) abolished almost totally negative chronotropic responses to
SAP and cervical vagus stimulation or negative dromotropic
responses to
AVP and cervical vagus stimulation, respectively
Haudek et al., Proc Natl Acad Sci U S A 2008
(Cardiomyopathies...) :
However, unlike wild-type mice,
SAP in FcRgamma ( -/- ) mice failed to inhibit the development of fibrosis and cardiac dysfunction and did not
diminish the numbers of alpha-smooth muscle actin ( + ) and
CD34 ( + ), CD45 ( + ) fibroblasts that were typical for I/RC
Li et al., Cell Signal 2008
(Lymphoproliferative Disorders) :
Expression of
SAP in the A20 B cell line
led to a marked reduction in
Blnk phosphorylation, a decrease in Akt activation, and a near-complete ablation of phosphorylation of the MAP kinases Erk1/2, p38 and JNK upon colligation of FcgammaRIIB with the B cell receptor (BCR) ... Expression of
SAP in the A20 B cell line
led to a marked reduction in Blnk phosphorylation, a decrease in
Akt activation, and a near-complete ablation of phosphorylation of the MAP kinases Erk1/2, p38 and JNK upon colligation of FcgammaRIIB with the B cell receptor (BCR)
Li et al., Cell Signal 2009
(Lymphoproliferative Disorders) :
Depletion of
SAP by siRNA
caused a significant decrease in
NCK1 tyrosine phosphorylation as well as the phosphorylation of other T cell receptor ( TCR ) downstream proteins such as LAT and SLP-76
Kamei et al., Journal of hepato-biliary-pancreatic sciences 2010
(Acute Disease...) :
TREM-1 may
act as an important mediator for inflammation and organ injury in
SAP
Pilling et al., PloS one 2009
:
In addition, IL-4, IL-12, IL-13, IFN-gamma, and
SAP differentially
regulate the expression of CD32,
CD163 , CD172a, and CD206 on both macrophages and fibrocytes ... In addition, IL-4, IL-12, IL-13, IFN-gamma, and
SAP differentially
regulate the expression of
CD32 , CD163, CD172a, and CD206 on both macrophages and fibrocytes ... In addition, IL-4, IL-12, IL-13, IFN-gamma, and
SAP differentially
regulate the expression of CD32, CD163, CD172a, and
CD206 on both macrophages and fibrocytes ... In addition, IL-4, IL-12, IL-13, IFN-gamma, and
SAP differentially
regulate the expression of CD32, CD163,
CD172a , and CD206 on both macrophages and fibrocytes
Enose-Akahata et al., PLoS Pathog 2009
(Paraparesis, Tropical Spastic) :
High expression of CD244 and
SAP regulated
CD8 T cell responses of patients with HTLV-I associated neurologic disease
Zhou et al., Hepatobiliary Pancreat Dis Int 2010
(Acute Disease...) :
We assessed the
effects of the inhibitor of
MCP-1 , Bindarit, on
SAP and explored the mechanisms underlying SAP
Yusuf et al., J Immunol 2010
:
These data illustrate complexities of
SAP dependent
SLAM family receptor signaling, revealing a prominent role for SLAM receptor ligation in IL-4 production by GC CD4 T cells but not in T ( FH ) cell and GC T ( FH ) cell differentiation
Verykokakis et al., Immunity 2010
:
Here we showed that Id3 ( -/- )
CD8 ( + ) T cells had an innate-like phenotype and
required SAP for their development
Pietrella et al., Infect Immun 2010
(Inflammation) :
In particular Sap1,
Sap2 , and Sap6 significantly
induced interleukin-1ß (IL-1ß) , tumor necrosis factor alpha ( TNF-a ), and IL-6 production ... In particular Sap1,
Sap2 , and Sap6 significantly
induced interleukin-1ß (IL-1ß), tumor necrosis factor alpha ( TNF-a ), and
IL-6 production
Mulder et al., J Alzheimers Dis 2010
(Alzheimer Disease) :
In conclusion, these data suggest that local production of
SAP and CRP in the AD brain does not substantially
contribute to the
CSF levels
Garlanda et al., Curr Pharm Des 2011
(Atherosclerosis...) :
CRP and
SAP are produced primarily in the liver in
response to
IL-6 , while PTX3 is produced by a variety of tissues and cells and in particular by innate immunity cells in response to proinflammatory signals and Toll-like receptor ( TLR ) engagement
Schwalbe et al., J Biol Chem 1990
:
Furthermore,
SAP had little or no effect on the ability of C4BP to bind
C4b
Mulder et al., Exp Neurol 2012
(Alzheimer Disease) :
Further,
SAP-C1q increased
SCARB1 expression in control astrocytes when combined with Aßoligo
Dang et al., Gastroenterology research and practice 2012
:
Severe acute pancreatitis (SAP) can
cause intestinal barrier dysfunction ( IBD ) , which significantly increases the disease severity and risk of mortality
Vitoriano-Souza et al., PloS one 2012
:
With regard to cytokines, the
SAP led to production of
interleukin (IL)-2 , IL-6, and IL-4 ... With regard to cytokines, the
SAP led to production of interleukin (IL)-2, IL-6, and
IL-4 ... With regard to cytokines, the
SAP led to production of interleukin (IL)-2,
IL-6 , and IL-4
Schmidt et al., Diabetes Technol Ther 2012
(Diabetes Mellitus, Type 1) :
Conclusions : This study documents persisting beneficial
effects of
SAP on
HbA1c , treatment satisfaction, magnitude of diabetes related problems, and fear of hypoglycemia 36 months after therapy start
Madapura et al., Cell cycle (Georgetown, Tex.) 2012
:
Modifying
p53 levels using Nutlin-3, which specifically dissociates the MDM2-p53 interaction, was
sufficient to upregulate
SAP expression, indicating that SAP is a target of p53 in T cells
Yang et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2013
(Disease Models, Animal...) :
To observe the effects of Qingyi Granule ( QYG ) on the changes of total protein expressions in the pancreatic tissue of rats with
severe acute pancreatitis (SAP) induced by
sodium taurocholate (STC)
Lin et al., Inflammation 1990
:
Purified mouse
interferon-beta (IFN-beta) , but not IFN-alpha, also
induced SAP production
Nogee et al., Am J Perinatol 1988
(Hyaline Membrane Disease...) :
SAP-35 expression is
enhanced by 3'-5'-cyclic adenosine monophosphate and
epidermal growth factor during perinatal differentiation of type II epithelial cells
Siripont et al., Cell Immunol 1988
:
Binding of
SAP to M phi
required Ca2+ or
Mg2+ and was inhibited at a pH less than or equal to 5.6 ... Binding of
SAP to M phi
required Ca2+ or Mg2+ and was inhibited at a pH less than or equal to 5.6
Ozkan et al., J Trauma 1987
:
Reversal of
SAP induced immunosuppression and
SAP detection by a monoclonal antibody
Sarlo et al., Cell Immunol 1985
:
The mouse macrophage line P388D1, also could bind SAP and display enhanced
IL-1 production in
response to
SAP
Korewicki et al., Cor Vasa 1985
(Coronary Disease...) :
The
effects of intravenous nitroglycerin ( NTG ), trimetaphan ( TMP ), and
phentolamine (PTL) on pulmonary artery diastolic pressure ( PADP ),
systemic arterial pressure (SAP) , cardiac index ( CI ) and systemic vascular resistance ( SVR ) in patients ( 12 in each treated group ) with chronic ischaemic heart failure are analyzed
Sipe et al., Ann N Y Acad Sci 1982
(Acute Disease...) :
Unlike SAA synthesis, BCG-preinfection fails to synergistically augment the
LPS induced
SAP response
Bugni et al., Am Heart J 1980
(Arterial Occlusive Diseases...) :
The
effect of mean
systemic arterial pressure (SAP) on myocardial O2 consumption ( MVO2 )
coronary blood flow (CBF) and the reduction of left ventricular ( LV ) reserve capacity resulting from coronary artery occlusion was studied in 25 open-chest pentobarbital anesthetized dogs with fixed cardiac output and controlled heart rate ( HR ) and SAP
Büscher et al., Mol Cell Biol 1995
:
Both
CSF-1 and LPS rapidly activate the MAPK network and
induce the phosphorylation of two distinct ternary complex factors ( TCFs ), TCF/Elk and
TCF/SAP ... Both CSF-1 and
LPS rapidly activate the MAPK network and
induce the phosphorylation of two distinct ternary complex factors ( TCFs ), TCF/Elk and
TCF/SAP
García de Frutos et al., J Immunol 1994
:
Even though C4BP, C4 ( H2O ), and SAP form a multimolecular complex in fluid phase,
SAP was found to
inhibit binding of
C4BP to immobilized C4 ( H2O ) ... Heparin, which is known to inhibit the interaction between SAP and C4BP, was also found to counteract the inhibitory
effect of
SAP on
C4BP binding to C4 ( H2O )
Ku et al., Cytokine 1993
(Carcinoma, Hepatocellular...) :
By contrast, gene expression of the major APR of the mouse,
serum amyloid P-component (SAP) , a structural homologue of CRP, increased in
response to either
IL-1 or IL-6 under the same conditions ... By contrast, gene expression of the major APR of the mouse,
serum amyloid P-component (SAP) , a structural homologue of CRP, increased in
response to either IL-1 or
IL-6 under the same conditions
Husøy et al., Carcinogenesis 1993
(Cell Transformation, Neoplastic) :
The
effects of 12-O-tetradecanoylphorbol-13-acetate ( TPA ), 12-deoxyphorbol-13-phenylacetate ( DOPP ), 12-deoxyphorbol-13-phenylacetate-20-acetate ( DOPP A ),
sapintoxin D (SAP D) and sapintoxin A (SAP A) on the decrease in [ 125I ] epidermal growth factor (EGF) binding ( indicating protein kinase C activation ), suppression of gap junctional intercellular communication ( GJIC ) and induction of
morphological cell transformation (MCT) in Syrian hamster embryo (SHE) cells were investigated
Tsai et al., J Biol Chem 1993
:
Binding of
ARF1 and -3, but not ARF5, was
enhanced by
SAP ... Binding of ARF1 and -3, but not
ARF5 , was
enhanced by
SAP ... B36, an inactive derivative of BFA, did not inhibit
SAP dependent binding of
ARF1 and -3
Molewijk et al., Psychopharmacologia 1995
:
The 5-HT2C/1B receptor agonist
m-CPP , the inverse BZD receptor agonists FG 7142 and DMCM, and the alpha 2-adrenoceptor antagonist yohimbine, to all of which putative anxiogenic effects have been ascribed,
had no effect on
SAP directed towards the prod
Zahedi et al., J Biol Chem 1996
:
Binding of
SAP to type IV collagen was
inhibited by both
SAP and C-reactive protein (CRP)
Zahedi et al., J Biol Chem 1997
:
Competition binding assays indicate that the binding of
SAP to laminin is
inhibited by both
SAP and its analog, C-reactive protein, as well as phosphatidylethanolamine ... Competition binding assays indicate that the binding of
SAP to laminin is
inhibited by both SAP and its analog, C-reactive protein, as well as
phosphatidylethanolamine
Whitmarsh et al., Mol Cell Biol 1997
:
In contrast,
SAP-1 is
activated by
ERK and p38 MAP kinases but not by JNK
de Haas et al., J Immunol 1998
:
In search for the LPS binding site of SAP, we found that
pep27-39 , a 13-mer peptide consisting of amino acids 27-39 of SAP, competitively
inhibited the binding of LPS to
SAP ... Performing gel filtration of FITC labeled ReLPS incubated with soluble CD14, we showed that
SAP could not
prevent binding of LPS to soluble
CD14 , in contrast to pep27-39 ... Performing gel filtration of FITC labeled ReLPS incubated with soluble CD14, we showed that
SAP could not
prevent binding of
LPS to soluble CD14, in contrast to pep27-39
Liedtke et al., Oncogene 1998
(Cell Transformation, Neoplastic) :
Regulation of
Bcr-Abl induced
SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase ... Regulation of
Bcr-Abl induced
SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase