Gene interactions and pathways from curated databases and text-mining

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SULT2A1 — TLR3

Text-mined interactions from Literome

Brint et al., Nat Immunol 2004 (Inflammation) : We show here that the membrane bound form of ST2 negatively regulated type I interleukin 1 receptor ( IL-1RI ) and Toll-like receptor 4 (TLR4) but not TLR3 signaling by sequestrating the adaptors MyD88 and Mal
Liew et al., Immunol Lett 2005 : We have recently demonstrated that the membrane bound form of ST2 ( ST2L ) negatively regulated IL-1RI and TLR4 but not TLR3 signaling by sequestrating the adaptors MyD88 and Mal
Feterowski et al., Int Immunol 2005 (Peritonitis) : While pre-treatment with MALP-2 does not involve differential expression of TLR and IL-1R associated kinase proteins, ST2 , a negative regulator of TLR signaling, was up-regulated after treatment of mice with either MALP-2 or N-alpha-palmitoyl-S- [ 2,3-bis ( palmitoyloxy ) - ( 2RS ) -propyl ] -L-cysteine