Gene interactions and pathways from curated databases and text-mining

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CASP8 — SYT1

Text-mined interactions from Literome

Kang et al., J Biol Chem 2001 : Our results suggest that NA induces apoptosis by the negative regulation of cell survival through caspase-3 mediated cleavage of p65
Wong et al., Clin Immunol 2006 : Fas ( CD95 ) ligation inhibits activation of NF-kappa B by targeting p65-Rel A in a caspase dependent manner
Stark et al., Carcinogenesis 2007 (Colorectal Neoplasms...) : Furthermore, we show that this response occurs in a time dependent manner and is paralleled by nuclear translocation of p65 and caspase activation
Wang et al., Chin J Cancer 2009 (Breast Neoplasms) : The cellular caspase-3 level was enhanced whereas the p65 level was decreased in celecoxib treated MDA-MB-231 cells after 24 h in comparison to those in the control cells