Verona et al., J Neurochem 2000
:
Stimulation of Ca2+/calmodulin dependent protein kinase II, which endogenously phosphorylates synaptotagmin in synaptic vesicles, increased the interaction of syntaxin and SNAP-25 with synaptotagmin ( particularly when measured in the presence of calcium ), as well as increasing the binding of the kinase itself
Lopez et al., FASEB J 2007
:
Previous studies indicate that the process requires Rab3 dependent tethering of membranes, SNARE complex assembly, and Ca2+ mediated activation of synaptotagmin