Gene interactions and pathways from curated databases and text-mining

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SNAP25 — SYT5

Pathways - manually collected, often from reviews:

  • Reactome Reaction: SYT5 → SNAP25 (direct_complex)

Text-mined interactions from Literome

Verona et al., J Neurochem 2000 : Stimulation of Ca2+/calmodulin dependent protein kinase II, which endogenously phosphorylates synaptotagmin in synaptic vesicles, increased the interaction of syntaxin and SNAP-25 with synaptotagmin ( particularly when measured in the presence of calcium ), as well as increasing the binding of the kinase itself
Lopez et al., FASEB J 2007 : Previous studies indicate that the process requires Rab3 dependent tethering of membranes, SNARE complex assembly, and Ca2+ mediated activation of synaptotagmin