McNiece et al., Blood 1989
(Carcinoma...) :
Replating experiments demonstrated that SF-1 plus CSF-1 generated HPP-CFC ( responsive to IL-3 plus CSF-1 ) ; however, IL-1 plus CSF-1 resulted in no generation of HPP-CFC McNiece et al., Exp Hematol 1987
:
HPP-CFC-2 are stimulated by CSF-1 plus interleukin-3 and generate macrophage CFC that differentiate to form mature macrophages
Stewart et al., Blood 1993
(Hodgkin Disease...) :
Multifactor combinations, especially GM-CSF + G-CSF + IL-3 + IL-6 + IL-1 + CSF-1 did not increase total colony count or classic HPP-CFC but did result in altered morphology, producing huge, loose colonies