Gene interactions and pathways from curated databases and text-mining

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BCL2 — TCF15

Text-mined interactions from Literome

Tamatani et al., J Biol Chem 1999 : To examine the possible involvement of a transcription factor , NFkappaB, in the regulation of Bcl-2 and Bcl-x expression in TNF treated neurons, an adenoviral vector capable of expressing a mutated form of IkappaB was used to infect neurons prior to TNF treatment
Budhram-Mahadeo et al., J Biol Chem 1999 : p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor
Glasgow et al., Neurochem Res 2000 (Neurodegenerative Diseases) : Key in these cascades is the activation of the caspase and Bcl-family of proteins by the NF-kappaB transcription factor
Freeland et al., Brain Res Mol Brain Res 2001 (Second Messenger Systems) : Despite the lack of cyclic AMP responsiveness, activation of the Bcl-2 promoter via the CRE in response to hypoxia requires the CREB transcription factor and is associated with the enhanced phosphorylation of CREB on serine 133 and enhanced transcriptional activation by the CREB binding protein, CBP, in response to hypoxia
Xie et al., Crit Rev Immunol 2006 : However, TCF-1 and ROR gamma t by themselves are not sufficient to stimulate Bcl-xL expression
Li et al., Oncogene 2007 (Colonic Neoplasms) : To examine the possible direct transcriptional regulation of rat Bcl-2 by beta-catenin/Tcf , we cloned and characterized the corresponding promoter region and found 70.1 % similarity with its human counterpart, BCL2
Gyamfi et al., J Pharmacol Exp Ther 2008 (Inflammation...) : Furthermore, signal transducer and activator of transcription factor ( STAT ) 3 and associated Bcl-xL induction was observed in ethanol fed wild-type mice but not in ethanol fed hepatocyte RXRalpha-deficient mice
Hornyak et al., Pigment Cell Melanoma Res 2009 : Microphthalmia associated transcription factor ( Mitf ) is essential for melanocyte development and function and regulates anti-apoptotic Bcl2 expression
Zhang et al., Asian Pac J Cancer Prev 2013 (Urinary Bladder Neoplasms) : Effect of Bcl-2 on apoptosis and transcription factor NF-?B activation induced by adriamycin in bladder carcinoma BIU87 cells
Smith et al., J Biol Chem 1998 : Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor