Gene interactions and pathways from curated databases and text-mining

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TECR — TNF

Text-mined interactions from Literome

Chakravortty et al., Microbiol Immunol 1999 : Overall, these results suggest that TNFalpha produced by HSILPF in response to LPS as a soluble form cause a decrease in the TER and loosening of tight junctions, and such early changes in the epithelial barrier may contribute to local inflammation in the gut
Zolotarevsky et al., Gastroenterology 2002 (Escherichia coli Infections...) : The data also suggest that TNF-alpha and IFN-gamma regulate TER , at least in part, via the perijunctional cytoskeleton
Resta-Lenert et al., Gastroenterology 2006 : Both TNF-alpha and IFN-gamma significantly reduced TER and increased epithelial permeability, effects prevented by ST/LA or BT. A Janus kinase ( JAK ) inhibitor synergistically potentiated effects of ST/LA or BT on TER and permeability, but p38, ERK1, 2, or PI3K inhibition did not
Kimura et al., Invest Ophthalmol Vis Sci 2008 : TNF-alpha induced a decrease in the TER of HCE cells in a concentration- and time dependent manner ... The NF-kappaB inhibitor curcumin blocked the effects of TNF-alpha on TER and the subcellular localization of ZO-1 at late phase
Shivanna et al., Molecular vision 2010 : Co-treatment, as well pre-treatment, with forskolin plus rolipram prevented the TNF-alpha induced decrease in TER
Peng et al., Journal of neuroinflammation 2011 : Moreover, depletion of PKC-a, of p115RhoGEF, and inhibition of RhoA activation also prevented TNF-a induced stress fiber formation and a decrease in TER
Shao et al., PloS one 2013 : Moreover, down-regulation of caveolin-1 attenuated TNF-a induced decrease in TER , increase in the flux of FITC-BSA and the disappearance of cortactin from the cell periphery in RPMVEC