Gene interactions and pathways from curated databases and text-mining

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TGFB1 — TLR5

Text-mined interactions from Literome

Liu et al., Mol Immunol 2008 : Endogenous transforming growth factor-beta1 ( TGF-beta1 ) plays an important role in the negative regulation of toll-like receptor ( TLR ) signaling in a feedback manner
Allam et al., J Allergy Clin Immunol 2008 : Moreover, TLR4-ligation on oLCs induced IL-10, TGF-beta1 , Forkhead box protein 3, IFN-gamma, and IL-2 production in T cells
Lee et al., Biochem Biophys Res Commun 2010 : Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-beta1 induced negative regulation of IL-1R/TLR signaling
Piconi et al., AIDS 2010 (HIV Infections) : Activated T cells ( Ki67 ( + ) ), Treg lymphocytes ( CD4 ( + ) /CD25high/Foxp3+ ), divided into naive and activated cells based on PD1 expression, interleukin (IL)-10 and transforming growth factor ( TGF ) -beta production, annexin V, activation of caspases 8 and 9, Toll-like receptor (TLR)2 and TLR4 expression on immune cells, and plasma lipopolysaccharide (LPS) concentration were analyzed
Brisbin et al., Benef Microbes 2012 : The results demonstrated that chicken CD4+ and CD8+ T-cells express TLR21 and that the various isolates of lactobacilli differentially induces the expression of interleukin 10, interferon-gamma and transforming growth factor beta